Clomiphene or Clomifene is the active substance in the brand Clomid (which can be found sold as many other trade names) and this is a SERM (Selective Estrogen Receptor Modulator) found in the same category as Tamoxifen (Nolvadex).
SERMs and Aromatase Inhibitors (AIs) together are considered anti estrogens, however they are very different in how they deal with estrogenic issues and mechanism of action.
- Clomid (Clomiphene Citrate) is mostly used in medical settings prescribed to women to induce ovulation and therefore increase pregnancy chances. Therefore, this is considered a fertility drug.
- Nonetheless, Clomiphene has been discovered to be very effective for male bodybuilders and athletes who are running androgenic and anabolic steroids (AAS).
In fact, it is very effective not for the cycle itself, but when the AAS cycle ends, because Clomid is a highly effective PCT (Post Cycle Therapy) drug for recovering the natural hormonal balance after the cycle.
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Clomiphene Citrate is effective in increasing total testosterone levels artificially, but the body produces testosterone itself. Those who cycle anabolic and androgenic steroids are getting their production of testosterone shut down, when they stop the administration of AAS, their levels of T remain low as the body requires months or even years to fully recover the ability to produce enough levels.
That’s why Clomid is such a popular PCT product – it reduces the time required to recover back this ability and maintains levels of testosterone high to avoid crashes (low T levels result in many nasty symptoms for a man).
Clomiphene Citrate During Post Cycle Therapy (PCT)
Clomid is a SERM and therefore it binds to the estrogen receptors similarly to Nolvadex (Tamoxifen Citrate) but they are still different and therefore, Nolvadex is way more powerful for gynecomastia treatment or prevention. Clomid is considered a weak anti-gynecomastia drug and is very rarely used for this purpose.
Instead, Clomid has great abilities to boost testosterone levels. That’s why it is an amazing PCT medication but due to boost in this hormone, is banned by WADA.
Why wouldn’t you use Clomid for boosting testosterone instead of anabolic steroids? Clomid is not an anabolic compound, it won’t be effective for making strength and muscle gains, plus is not recommended to be used for such needs due to how it works, side effects etc.
How Exactly Clomiphene Works?
It has the same mechanism of action that is helpful both for women who want to ovulate and increase pregnancy chances as well as for men who need Clomid for Post Cycle Therapy.
Clomid boosts LH and FSH. It doesn’t mimic it as other compounds and therefore suppresses them. It actually increases LH and FSH. Clomiphene does so by stimulating the hypothalamus into releasing more gonadotropins.
- More Gonadotropins results in more LH and FSH and more LH and FSH results in more testosterone.
It does so by blocking the estrogen at your pituitary gland. A part of testosterone is converted into estrogen in the body and estrogen is signaling pituitary to stop making LH and therefore it stops making testosterone. Clomiphene is blocking the estrogen at pituitary and it produces more LH and more Testosterone.
When you use Testosterone – your body “thinks” too much testosterone is produced by itself, that’s why it stops the production.
Clomiphene Citrate Administration
Clomiphene half life is about 6 days (different sources offer different results such as 5 days or 7 days). You need to use it on a daily basis in order for the compound to build up in the system. Once a day administration (same time of the day) is going to be perfect.
Dosage of Clomid for PCT depends on how bad your cycle was. If you need it for medical purposes – talk with your doctor. But Clomid PCT usually is around 50 mg a day for 2 weeks in PCT and 25 mg a day for the last 2 weeks in PCT (total 4 weeks).
PCT plans usually run between 3 and maximum 8 weeks, 4 weeks being most common.
If you have a harsher cycle, go for 100 mg a day first weeks. Some people go up to 200 mg a day which is too much for most people. Anything over 200 mg a day of Clomiphene is abuse.
Dosages for PCT of Clomid are started higher, then are slowly reduced (because right after the cycle you need more testosterone and then you recover back).
Side effects are possible such as emotional, vomiting, mood swings, etc. But remember that Clomiphene Citrate is used to deal with side effects, not to offer you new ones.
Most commonly, Clomiphene is stacked with Tamoxifen for PCT.
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